"Both perspectives, pessimism and existentialism, wouldn't necessarily see depression as a malady existing in a person's head. A pessimist and existentialist might, in fact, agree that the world itself is screwed up, that social norms are themselves pathological, that feelings of despair, anxiety, loss, and pointlessness may be typical in people who are exceptionally intelligent and observant."
"Philosophers such as John Stuart Mill, William James, and Friedrich Nietzsche suffered the worst throes of depression. A host of other artists and writers suffered the same fate, including Edgar Allen Poe, William Blake, Mark Twain, Wolfgang Mozart, Charles Dickens, Vincent Van Gogh, T.S. Eliot, Ernest Hemingway, and Sylvia Plath."